Ground glass hepatocyte

E nder patoloji heeñere, hepatosit gilaas leydi, ko GGH, ko ƴiiƴam parenkiima heeñere, jogiiɗam sitoplasma ɓuuɓɗo, ɓuuɓɗo no feewi, e dow mikroskoop annoore. Ko woodgol HBsAg addata ɓuuɓri eosinofilik homojeneeji ɓuuɓɗi e nder sitoplasma.

Feññinde ina jokkondiri e antigen hepatitis B keewɗo e nder retikulum endoplasma, kono ina waawi kadi wonde ko ñawu nguu addata ɗum. E nder ngonka hepatitis B, GGH ina yiyee tan e ñawuuji gonɗi e nder ɓalndu, ɗum woni ɗi njiyataa e hepatitis B ɓuuɓɗo.

GGHs ko Hadziyannis e woɗɓe adii siftinde ɗum en.

Fannuuji

Nokkuuji GGH keewɗi ceertuɗi ina nganndaa :

Sifaa I - e morfolooji ina waɗi GGHs cirƴaaɗi gooto gooto, jogiiɗi immunostaining moƴƴo Pre-S2 mo alaa ko waawi.

Sifaa II - e morfolooji ina waɗi GGHs gonɗi e nder ɓuuɓri, jogiiɗi immunostaining Pre-S2 mo alaa ko woni e mum.

Won ko holliti wonde GGHs mo sifaa II ina waawi saabaade kanseer hepatosellulaar.

Ƴeew kadi

Jaabawol leɗɗe

Mallory ɓanndu

Hepatitis viral

Nate ɓeydaaɗe

Mikrogaraam holliroowo hepatositteeji gilaas leydi. H&E taƴre.

Tuugnorgal^[1] ^[2]^[3]^[4]

↑ Cohen, C (Aug 1975). ""Ground-glass" hepatocytes". S Afr Med J. 49 (34): 1401–3. PMID 1162516.
↑ Su, IJ; Wang, HC; Wu, HC; Huang, WY (Aug 2008). "Ground glass hepatocytes contain pre-S mutants and represent preneoplastic lesions in chronic hepatitis B virus infection". J Gastroenterol Hepatol. 23 (8 Pt 1): 1169–74. doi:10.1111/j.1440-1746.2008.05348.x. PMID 18505413.
↑ Cite error: Invalid <ref> tag; no text was provided for refs named pmid185054132
↑ Abe, K; Thung, SN; Wu, HC; Tran, TT; Le Hoang, P; Truong, KD; Inui, A; Jang, JJ; Su, IJ (Aug 2009). "Pre-S2 deletion mutants of hepatitis B virus could have an important role in hepatocarcinogenesis in Asian children". Cancer Sci. 100 (12): 2249–54. doi:10.1111/j.1349-7006.2009.01309.x. PMC 11159494 Check |pmc= value (help). PMID 19719772. S2CID 38459908.

[pmid1162516-1] Cohen, C (Aug 1975). ""Ground-glass" hepatocytes". S Afr Med J. 49 (34): 1401–3. PMID 1162516.

[pmid18505413-2] Su, IJ; Wang, HC; Wu, HC; Huang, WY (Aug 2008). "Ground glass hepatocytes contain pre-S mutants and represent preneoplastic lesions in chronic hepatitis B virus infection". J Gastroenterol Hepatol. 23 (8 Pt 1): 1169–74. doi:10.1111/j.1440-1746.2008.05348.x. PMID 18505413.

[pmid185054132-3] Cite error: Invalid <ref> tag; no text was provided for refs named pmid185054132

[pmid19719772-4] Abe, K; Thung, SN; Wu, HC; Tran, TT; Le Hoang, P; Truong, KD; Inui, A; Jang, JJ; Su, IJ (Aug 2009). "Pre-S2 deletion mutants of hepatitis B virus could have an important role in hepatocarcinogenesis in Asian children". Cancer Sci. 100 (12): 2249–54. doi:10.1111/j.1349-7006.2009.01309.x. PMC 11159494 Check |pmc= value (help). PMID 19719772. S2CID 38459908.

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