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Pleomorphism (cytology)

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Pleomorfism ko helmere huutorteende e nder histoloji e sitopatoloji ngam siftinde waylo-waylo mawneeki, mbaadi e mbaydi ƴiye e/walla ƴiye mum en.  Ko heewi e ko anndinta mawnugol taklon e nukliyeer, ko wayi no ploidi e reentaade mbayliigu taklon, ina keewi bonnude e nder ɓuuɓri.[1]  Ko ɗum waɗi, pleomorfism cellal e nukliyeer ina jeyaa e ko ɓuri teeŋtude e maale ƴellitaare kanseer, kadi ko sifaa sifaa neoplasmaaji bonɗi e displaasi. [1][2]Won e mbaydiiji cellal moƴƴi ina mbaawi kadi hollirde pleomorfism, e.g.  ƴiye gonɗe e nder ɓalndu, ko mbaydi Arias-Stella.

Sifaa rabdomiosarkoma mo heewaani yiyeede e mawɓe ina wiyee rabdomiosarkoma pleomorfik.[4]

Pleomorfisme fof e heewde e nder pathogenesis aadee, darnde mum e yahrude yeeso ñawu nguu laaɓtaani.  E nder ƴiiƴam epiteliyal, pleomorfism e nder mawneeki cellal ina waawi addande ŋakkeende paaspoor e saaktude cellal mbaylaandi.[5]  Kono batte morfolooji cellal e nukkuur atypique e nder ƴiye goɗɗe anndaaka.

Anaplaasi

Mawnugol cellal

Sitopatoloji

Kanser cellal mawɗo e nder ƴiiƴam

Atipiya nukliyeer

  1. Travis, W.D.; Brambilla, B.; Burke, A.P; Marx, A.; Nicholson, A.G. (2015). WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart. Lyon: International Agency for Research on Cancer. ISBN 978-92-832-2436-5. Archived from the original on March 21, 2015.
  2. El-Naggar, A.K.; Chan, J.C.K.; Grandis, J.R.; Takata, T.; Slootweg, P.J. (23 January 2017). WHO Classification of Head and Neck Tumours. Lyon: International Agency for Research on Cancer. ISBN 978-92-832-2438-9. Archived from the original on 2019-10-31. Retrieved 2019-10-31.