Jordi Folch Pi
| Jinsu | gorko  |
|---|---|
| Ɓii-leydiyankaaku | Hispaanya |
| Innde | Jordi |
| Ɗuubi daygo | 25 Mbooy 1911 |
| Ɗoforde | Barcelona |
| Date of death | 3 Yarkomaa 1979 |
| Place of death | Boston |
| Father | Rafael Folch i Capdevila |
| Mother | Maria Pi Ferrer |
| Sibling | Albert Folch i Pi, Núria Folch i Pi |
| Ɗemngal | Catalan |
| Wolde | Catalan, Spanish, Inngilisjo |
| Sana'aji | biochemist |
| Employer | Harvard University |
| Janngi to | University of Barcelona |
| Memba en | National Academy of Sciences, Instituto de Estudios Catalanes, Royal Academy of Medicine of Catalonia |
| Award received | honorary doctor of the Autonomous University of Barcelona, honorary doctorate of the University of Montpellier |
Jordi Folch Pi (25 mars 1911 – 3 oktoobar 1979) ko biyokimist Espaañnaajo to duɗal jaaɓi haaɗtirde Harvard (Opitaal McLean) ganndiraaɗo e winndere ndee kala wonde gooto e sosɓe fannu kemikal mbaydiiji lipiduuji caɗtuɗi, kadi ko gardiiɗo ƴellitaare e neurochemistry ko fannu ceertuɗo e nder gannde neuro.
Ɓiɗɗo
[taƴto | taƴto ɗaɗi wiki]Folch jibini nder Barcelona, Spain. Baaba maako, Rafel Folch, o laamiiɗo e mawɗo Catalan, nden inna maako, Maria Pi, o jannginoowo. Folch yahi nder jaŋde nder Lisle Faransi nder Barcelona, nde o jaŋde e hitaande 1927. O yahi janngude medicine, o heɓii M.D. degree diga University of Barcelona Medical school e 1932.
Fuɗɗam golle
[taƴto | taƴto ɗaɗi wiki]Folch's training clinical at university hawti e wakkati nde o wondi mo'o mo'o ha suudu ndun ha doktoor Antoni Trias e nde o wonnoo mo'o doktoor tan e Almedret, wuro Catalan je ɗon woodi yimɓe 800. Folch woodi fursatinde janngude e Institute of Physiology e Barcelona, suudu je ɗon waɗugo kuugal kuugal kugal ngal naftoraaki laabi e miijooji jamanuɓe, nden Yeesu Mari Bellido e ammuugo Folch August Pi Sunyer njooɗi ɗum. O huwti bana walliɗo to ɓikkoy maako Cesar Pi Sunyer nden wakkati o heɓii M.D. degree maako, ɓe ɗon haɓɓiri e nder goɗɗe kuugaluuji nayi dow glycogen synthesis nder ɗemɗe tati feere feere (Jamani, Farayse, e Sipaani). Folch ɗon janngina boo ƴiiƴam glucose e metabolism lactic acid nder jaango neɗɗo mo o laatii mo annduki, Farasoore Rosend Carrasco Formiguera. Folich'en nder Institute of Physiology ɓeydi ɓeydi anndal maako nder physiology e nder dowlaaku bana bana bana bana boo, bana no ɓe hawti bee caɗeele metabolism. Ngam daliila hawtaade Carrasco, Francisco Duran Reynals, biochemist to Rockefeller Institute to New York, ɓeydi yiɗi Folch, o waɗi mo haa o wari nder suudu ndu bana mo yiɗi.[1]
Nder hitaande 1936, ɓaawo konu lesdi Spain fuɗɗi, o jaɓaama ngam annduki dow Rockefeller Institute nder New York, o jaɓi kuugal. E dow dow dow yimɓe mum (ko'o haɓɓi ngam partijo Republican ɓe ɓe ɓe ɓe maɓɓi - sakiraaɓe maako Albert e Nuria ɓe njaaraama to Mexico, ɓii maɓɓe Frederic boo waɗi lebbi seɗɗa nder kaso caggal nde o wari diga leydi Farayse), o waɗi anniya jooɗugo nder United States caggal nde konu leydi ndii timmi.
Tawee to Amerik
[taƴto | taƴto ɗaɗi wiki]Folch wari haa Rockefeller nder 1936 bana mo walliɗo. Nder hitaande ɓaawo nde o heɓii darnde dow darnde dow laamorde Donald Van Slyke. Folch'en arande nder suudu Rockefeller haani nder nder nder nder doktoor Irvine Page dow halleende hormone nder pituitary. Fola Folch haani jaɓugo ɓalli plasma nder nyauɓe ɗi. O ɗon faamani ngam ɓeydaaki naftoraaki ɓeydaaku ngam naftoraaki naftoraaku woodi caɗeele ngam ɓeydagol ngol walaa ɗuuɗal e ɓeydaako ɗon hawta ɓeydaago ɓeydaaka ɓeydaamu. O waɗi laawol ngol hawti e ɓanngol lipids e proteins bee colloidal iron e ƴettirde ɓurɗe ɓurɗe ɗuuɗugo non-lipid bee ndiyam, ɗum haɓɓii caɗeele ɓanngondiral.
Nder kuuje fuɗnde ɗe o wurtini dow kuugal bee Donald Van Slyke dow laawol manometric ɓeydi ngam jaɓɓude carbon. E huutoreede laawol ɓesngu ɓesngu, o holliti "cephalin" ɓesngu ƴiiƴam ɓernde nde caggal Johannes Thudichum (koɗo fuɗɗiiɗo nder karnijum sappo e jeegooji e sappo e njoweetati nder fannuuji neurochemistry) laatii phosphatidyl ethanolamine laaɓtu. Folch holli wonde ɗuuɗal carbon e amines naa' ɗon haani e formula Thudichum. Ɗuum kuudi waɗi Folch's fuɗnaaku dow lipids nder ɓernde nder 1941 nden fuɗnaaki nder wakkati duuɓi ɗuuɗɗi ngam hollaade dow cephalin naa' ko lipid go'oto, ammaa ko hawtaaki lipids tati (phosphatidyl ethanolamine, phosphatidyl serine, e inositol). Folch woni arandeejo mo hollitii darnde serine fosfatidil. Ɓeydi noon, o wurtini mono-, di- e triphosphoinositides.
Nder hitaande 1944, Folch laatii darinoowo dooktargal kuugal wiɗtooji njanngooji e nder suudu ndun McLean (divisiyon Massachusetts General Hospital) e jannginoowo janngooji dow kiimiya e nder Harvard Medical School ngam ɓamtaade kuugal nder Neuroscience. Fillasaaku maako ɓurnaandu woni, ngam faamugo kemistriji ɓernde, ɗum haani anndugo fuu ko ɓernde. Nder hitaande 1947 Marjorie Lees hawti bee maako, ɓe ɓamta kuuɗe laaɓuɗe ngam ɓamtuki ɓernde ɓernde ɓanndu ɓanndu ngam laawol kalluɗum ngam huutore hawtaaki hawtaaki cembiɗol chloroform-methanol e ɓamtuki fuɗɗam bee ndiyam, ngam ɗum waɗi ɓamtuki ɗuuɗal ɓanndu fuɗɗam e ƴiɓɓugo ɓannduji ɓannduɗi. Ɗuum laabi laati go'o nder kubaruuji ɓurɗi anndugo nder duuɓi 1950'en, e nder hitaande 2014 o wondi dow 9 nder nder kubarɗe ɓurɗe anndugo nder taariha anndal. Fannu ngal o ɓamta ngam laaɓugo ɓernde ɓernde ɓannduɓe ɓernde ɗon wi'a "Foliing" nden woni go'oto nder defte ɓurɗe wi'aade nder taariika biyokimiya.[1] Foolch solution ko foolololol haandi chloroform e methanol, ko adii e 2: 1 (vol/vol) ratio. Gooto nder huutoreeji mum ɗon haɓɓugo polar diga compounds nonpolar, misaalu haɓɓugo lipids nonpolar diga protein polar e carbohydrates nder serum ƴiiƴam. Ɓurɗe ɓeydaade, ko'e wi'aama ko'e maɓɓe ɓeydiima sabu hawtaade e laaɓal ngal nder ɗemngal Farayse bana "To Folch" ngam hollaade laaɓal Folch ngam jaɓugo ɓesngu.[2]
Folch huwti laawol maako ngam lartol waylitol nder ɓernde lipids e proteins nder ɓamtaare walla nyau. Nder kawtal e Lees ɓe naftiri laawol maɓɓe ngam heɓugo proteolipid miyelin (nganndi bana tippooji lipoprotein keso) nder huunde laaɓnde ndiyam e glycolipids (nganndaama strandin saa'i maajum, ammaa jooni anndiraa bana gangliosides) nder huunde cuka. Haa fuɗɗam golle maako, anndal proteolipids laatiima ɓurna kuuɗe e ɓernde Folch. Fasal foolch' e foolch fooldi dow jaayndiji ɓaawo ɗon dow proteine acylated e gangliosides.
Folch ina haani wonde gooto e ardiiɓe kemistri limle ɓaleeɓe e nder nder nder nder limle ɓernde. O wondi gooto e ardiiɓe American Society for Neurochemistry e International Society for Neurochemistry.[1] Nder 1956, Folch laati Farasisaajo Neurochemistry arande nder Harvard Academy of Arts and Sciences. E hitaande 1978, o suɓii nder National Academy of Sciences nder leydi Amerika.[1] O ɗon jeyaa e nder jaango jaango nder jaango nder Jaango nder Barcelona, o jeyaa e jaango nder nder jaango dow Montpellier, Faransi, e jaango dow jaango nder Chile, Santiago. Caggal nde o jeyi nder hitaande 1977, o jeyi o jeyi e nder jannginoowo neurochemistry emeritus e o jeyi haa o jeyi.[1]
Innde
[taƴto | taƴto ɗaɗi wiki]Innde makko nden ɗon yi'a nder ɓernde ("Folch-Pi"). Nder aada Espaañ ngam hokkude tagdi ɗiɗi, o ɗon foondira bee innde baaba maako e innde maako. Nde o dilli Amerika o ware, o waɗi anniya o wurtina innde maako e innde maako, ngam ɓiɓɓe maako mbaɗata ko o mari dow baaba maako: "Folch-Pi". Innde makko nden ɗon kootere "Foltsch Pie" ko "Folk Pie" amma kootoye Catalan ko "Folch Pea".
Nolde hoore
[taƴto | taƴto ɗaɗi wiki]Fedde e teddungal
[taƴto | taƴto ɗaɗi wiki]- Yimɓe Academy of Arts and Sciences Amerik (1956).
- Yimɓe Amerik National Academy of Sciences (1978).
- Professoratal honoris causa e dow Fedde Fedde Fuuta e Jaŋde Barcelona (Spain).
- Daraje teddungal dow jaŋde Montpelier (Faransiya).
- Daraje honoreeji diga jaŋde Chile, Santiago (Chile).
- Medal dow darnde darnde darngal CSIC (Supreme National Council for Scientific Research, Spain).